Oscar Isaac

as Nick / Dante

Gal Gadot

as Giulietta / Gemma

Gerard Butler

as Louie / Pope Bonifacio

John Malkovich

as Joe Black

Louis Cancelmi

as Lefty / Guido Novello Da Polenta

Sabrina Impacciatore

as Dr. Susanna Pulice

Franco Nero

as Don Lecco (86)

Benjamin Clementine

as Mephistopheles