John Wayne

as Lt. Col. Kirby Yorke

Maureen O'Hara

as Mrs. Kathleen Yorke

Ben Johnson

as Trooper Travis Tyree

Claude Jarman Jr.

as Trooper Jefferson 'Jeff' Yorke

Harry Carey Jr.

as Trooper Daniel 'Sandy' Boone

Chill Wills

as Dr. Wilkins

J. Carrol Naish

as Lt. Gen. Philip Sheridan

Victor McLaglen

as Sgt. Maj. Timothy Quincannon