Salma Hayek Pinault

as Frida Kahlo

Alfred Molina

as Diego Rivera

Mía Maestro

as Cristina Kahlo

Patricia Reyes Spíndola

as Matilde Kahlo

Edward Norton

as Nelson Rockefeller

Antonio Banderas

as David Alfaro Siqueiros

Diego Luna

as Alejandro

Roger Rees

as Guillermo Kahlo