Woody Harrelson

as One Eyed Jack Faro

Werner Herzog

as The German

Dennis Farina

as L.B.J. Deuce Fairbanks

David Cross

as Larry Schwartzman

Cheryl Hines

as Lainie Schwartzman

Richard Kind

as Andy Andrews

Chris Parnell

as Harold Melvin

Jason Alexander

as Dr. Yakov Achmed