Ross Bagdasarian Jr.

as David Seville / Alvin Seville / Simon Seville (voice)

Janice Karman

as Theodore / Brittany / Jeanette / Eleanor (voice)

Dody Goodman

as Miss Rebecca Miller (voice)

Susan Tyrrell

as Claudia Furschtien (voice)

Anthony De Longis

as Klaus Furschtien (voice)

Frank Welker

as Sophie / Native Chief / Baby Penguin / Additional Voices (voice)

Nancy Cartwright

as Arabian Prince (voice)

Philip L. Clarke

as Additional Voices (voice)