Spencer Tracy

as Dr. Henry 'Harry' Jekyll / Mr. Hyde

Ingrid Bergman

as Ivy Peterson

Lana Turner

as Beatrix 'Bea' Emery

Donald Crisp

as Sir Charles Emery

Ian Hunter

as Dr. John Lanyon

Barton MacLane

as Sam Higgins

C. Aubrey Smith

as The Bishop

Peter Godfrey

as Poole