Ross Bagdasarian Jr.

as Alvin Seville / Simon Seville / Dave Seville (voice)

Dee Bradley Baker

as Tour Guide (voice)

Michael Bell

as Dr. Frankenstein (voice)

Mary Kay Bergman

as Mother (voice)

Janice Karman

as Theodore Seville (voice)

Jim Meskimen

as Mr. Yesman (voice)

Kevin Michael Richardson

as Bud Wiley (voice)

Frank Welker

as The Monster (voice)