Charles Bronson

as Joe Valachi

Lino Ventura

as Vito Genovese

Jill Ireland

as Maria Reina Valachi

Walter Chiari

as Dominick Petrilli, aka "Gap"

Joseph Wiseman

as Salvatore Maranzano

Gerald S. O'Loughlin

as Ryan, federal agent

Amedeo Nazzari

as Gaetano Reina

Fausto Tozzi

as Albert Anastasia