Toshirō Mifune

as Dr. Kyojio Niide ("Red Beard")

Yūzō Kayama

as Dr. Noboru Yasumoto

Tsutomu Yamazaki

as Sahachi

Reiko Dan

as Osugi

Miyuki Kuwano

as Onaka

Kyōko Kagawa

as Madwoman ("The Mantis")

Tatsuyoshi Ehara

as Genzô Tsugawa

Terumi Niki

as Otoyo