Gloria Swanson

as Sadie Thompson

Lionel Barrymore

as Alfred Davidson

Blanche Friderici

as Mrs. Alfred Davidson

Charles Lane

as Dr. Angus McPhail

Florence Midgley

as Mrs. Angus McPhail

James A. Marcus

as Joe Horn

Sophia Artega

as Ameena

Will Stanton

as Quartermaster Bates