James McAvoy

as Patricia / Dennis / Hedwig / The Beast / Barry / Heinrich / Jade / Ian / Mary Reynolds / Norma / Jalin / Kat / B.T. / Kevin Wendell Crumb / Mr. Pritchard / Felida / Luke / Goddard / Samuel / Polly

Bruce Willis

as David Dunn / The Overseer

Samuel L. Jackson

as Elijah Price / Mr. Glass

Sarah Paulson

as Dr. Ellie Staple

Anya Taylor-Joy

as Casey Cooke

Spencer Treat Clark

as Joseph Dunn

Charlayne Woodard

as Mrs. Price

Luke Kirby

as Pierce