Jamie Foxx

as Joe Gardner (voice)

Tina Fey

as 22 (voice)

Graham Norton

as Moonwind (voice)

Rachel House

as Terry (voice)

Alice Braga

as Counselor Jerry (voice)

Richard Ayoade

as Counselor Jerry (voice)

Phylicia Rashād

as Libba Gardner (voice)

Donnell Rawlings

as Dez (voice)