Gian Maria Volonté

as Charles 'Lucky' Luciano

Vincent Gardenia

as Colonel Charles Poletti

Edmond O'Brien

as Commissioner Harry J. Anslinger

Rod Steiger

as Gene Giannini

Silverio Blasi

as Italian Captain

Charles Cioffi

as Vito Genovese

Larry Gates

as Judge Herlands

Magda Konopka

as Contessa