Michelle Pfeiffer

as Melanie Parker

George Clooney

as Jack Taylor

Mae Whitman

as Maggie Taylor, Jack's daughter

Alex D. Linz

as Sammy Parker, Melanie's son

Charles Durning

as Lew, Jack's boss

Jon Robin Baitz

as Mr. Yates, Jr.

Ellen Greene

as Mrs. Elaine Lieberman

Amanda Peet

as Celia