Eddie Murphy

as Sherman Klump / Buddy Love / Lance Perkins / Papa Klump / Mama Klump / Grandma Klump / Ernie Klump

Jada Pinkett Smith

as Carla Purty

James Coburn

as Harlan Hartley

Larry Miller

as Dean Richmond

Dave Chappelle

as Reggie Warrington

John Ales

as Jason

Patricia Wilson

as Dean's Secretary

Jamal Mixon

as Ernie Klump, Jr.