Johnny Depp

as Donnie Brasco / Joseph D. 'Joe' Pistone

Al Pacino

as Benjamin 'Lefty' Ruggiero

Michael Madsen

as Dominick 'Sonny Black' Napolitano

Bruno Kirby

as Nicholas 'Nicky' Santora

James Russo

as Paulie

Anne Heche

as Maggie Pistone

Željko Ivanek

as Tim Curley

Brian Tarantina

as Bruno